Dr. William Gaetz

Principal Investigator
Research Assistant Professor of Radiology
Department of Radiology, Perelman School of Medicine, University of Pennsylvania

There is growing interest in the study of cortical oscillations and the dependence of these cortical responses (frequency, power, etc.) on associated neurotransmitters such as glutamate and GABA as well as neuroanatomy via sMRI. Using multi-modal measures (MEG,MRS spectroscopy and sMRI) I feel we can gain a rich understanding of the neurobiology of cortical function in health and disease. For the past 16 years, I have used MEG/MRI/MRS methods to study neural function/structural correlates in children with a special focus on sensory and motor processes.

Email: gaetzw [at] email.chop.edu

Related Publications

  • Synthetic aperture magnetometry and excess kurtosis mapping of Magnetoencephalography (MEG) is predictive of epilepsy surgical outcome in a large pediatric cohort.

    Gofshteyn JS, Le T, Kessler S, Kamens R, Carr C, Gaetz W, Bloy L, Roberts TPL, Schwartz ES, Marsh ED. Epilepsy Res. 2019 Sep;155:106151. doi: 10.1016/j.eplepsyres.2019.106151. Epub 2019 Jun 17. PMID: 31247475

  • Abnormal maturation of the resting-state peak alpha frequency in children with autism spectrum disorder.

    Edgar JC, Dipiero M, McBride E, Green HL, Berman J, Ku M, Liu S, Blaskey L, Kuschner E, Airey M, Ross JL, Bloy L, Kim M, Koppers S, Gaetz W, Schultz RT, Roberts TPL. Hum Brain Mapp. 2019 Aug 1;40(11):3288-3298. doi: 10.1002/hbm.24598. PMID: 30977235

  • Magnetoencephalography and the infant brain

    Chen YH., Saby J., Kuschner E., Gaetz W., Edgar JC., Roberts TPL. Neuroimage, 2019, 189:445-458. doi: 10.1016/j.neuroimage.2019.01.059. PMID: 30685329

  • Gaetz W, Edgar JC, Wang D-J, Roberts TPL (2011). Relating MEG Measured Motor Cortical Oscillations to resting gamma-Aminobutyric acid (GABA) Concentration. NeuroImage, 2011 Mar 15;55(2):616-21.
  • Gaetz W., Bloy L., Wang DJ, Port RG, Blaskey LM, Levy SE, Roberts TPL (2014). GABA estimation in the Brains of Children on the Autism Spectrum: Measurement precision and regional cortical variation. Neuroimage 86,1-9.
  • Amaral S, Kessler, SK, Levy T, Gaetz W, et al., (2017). 18 Month Outcomes of Heterologous Bilateral Hand Transplantation in a Child: A Case Report. The Lancet Child & Adolescent Health. (In Press).
  • Gaetz W., Jurkiewicz M, Kessler S., Blaskey L, Schwartz E., Roberts T.P. (2017). Neuromagnetic responses to tactile stimulation of the fingers: Evidence for reduced cortical inhibition for children with autism spectrum disorder (ASD) and children with epilepsy. NeuroImage: Clinical (In Press)